Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)


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Chem n tonic strain

In addition, molecular modeling studies, which evaluated their modes of MAO inhibition, are presented. These findings could provide pivotal implications in the quest of novel drug-like compounds and for the establishment of harmful drug—dietary supplement interactions commonly reported in the therapy with antidepressant agents.

Table 1S, theoretical affinities of the selected flavonoids for the hMAOs. Food Chem. View Author Information. Germaneto, Catanzaro, Italy. Moro 5, Rome, Italy. Cite this: J. Article Views Altmetric -. Citations Supporting Information. Cited By.

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This article is cited by 30 publications. Journal of Agricultural and Food Chemistry , 66 30 , DOI: Journal of Agricultural and Food Chemistry , 66 27 , International Journal of Molecular Sciences , 20 10 , Current Topics in Medicinal Chemistry , 19 2 , Rhamnocitrin isolated from Prunus padus var. Bioorganic Chemistry , 83 , Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity.

Molecules , 24 6 , Neuroprotection of multifunctional phytochemicals as novel therapeutic strategy for neurodegenerative disorders: antiapoptotic and antiamyloidogenic activities by modulation of cellular signal pathways. Future Neurology , 14 1 , FNL9. BioMed Research International , , CyanidinO-glucoside inhibits different enzymes involved in central nervous system pathologies and type-2 diabetes. South African Journal of Botany , , Journal of Enzyme Inhibition and Medicinal Chemistry , 34 1 , Keith F. Journal of Neural Transmission , 11 , Hydroxyl-related differences for three dietary flavonoids as inhibitors of human purine nucleoside phosphorylase.

International Journal of Biological Macromolecules , , Molecules , 23 9 , Nabavi, Silvia Tejada. Current standing of plant derived flavonoids as an antidepressant. Food and Chemical Toxicology , , Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid. Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.

European Journal of Medicinal Chemistry , , Neurochem Int — Veech RL. The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.

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Prostaglandins Leukot Essent Fatty Acids — The ketogenic diet and brain metabolism of amino acids: relationship to the anticonvulsant effect. Annu Rev Nutr — Nutrition — Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester. J Lipid Res — Neurobiol Aging 34 6 —9. Alzheimers Dement — Curr Alzheimer Res 15 13 — The ketogenic diet as a treatment paradigm for diverse neurological disorders. Front Pharmacol Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study. Neurology 64 4 — How can a ketogenic diet improve motor function?

Front Mol Neurosci Failure of ketogenic diet therapy in GLUT1 deficiency syndrome. Eur J Paediatr Neurol in press. Klepper J, Leiendecker B. Glut1 deficiency syndrome and novel ketogenic diets. J Child Neurol 28 8 —8. Veggiotti P, De Giorgis V. Dietary treatments and new therapeutic perspective in GLUT1 deficiency syndrome. Curr Treat Options Neurol 16 5 Elsevier, Chapter 47 Non-toxic metabolic management of metastatic cancer in VM mice: novel combination of ketogenic diet, ketone supplementation, and hyperbaric oxygen therapy.

MAOIs: Overview & History - Psychotropical

PLoS One e A systematic review of the use of ketogenic diets in adult patients with cancer. J Hum Nutr Diet 31 6 — Adenosine A1 receptor antagonism abolished the anti-seizure effects of exogenous ketone supplementation in Wistar Albino Glaxo Rijswijk rats. Ketone bodies in epilepsy. J Neurochem — The current status of the ketogenic diet in psychiatry. Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature. Nutr Metab Lond A pilot study of the ketogenic diet in schizophrenia.

Am J Psychiatry —1. Ketogenic diet for schizophrenia: nutritional approach to antipsychotic treatment. Med Hypotheses —7. Palmer CM. Ketogenic diet in the treatment of schizoafective disorder: two case studies. Schizophr Res —9. The ketogenic diet and remission of psychotic symptoms in schizophrenia: two case studies.

Schizophr Res in press. Medium chain triglyceride diet reduces anxiety-like behaviors and enhances social competitiveness in rats. Brain Behav 5 2 :e The ketogenic diet modifies social and metabolic alterations identified in the prenatal valproic acid model of autism spectrum disorder. Dev Neurosci 36 5 — Metabolic dysfunction underlying autism spectrum disorder and potential treatment approaches.

Application of a ketogenic diet in children with autistic behavior: pilot study. J Child Neurol 18 2 —8.

Early Life Stress, Depression And Parkinson’s Disease: A New Approach

Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder. PLoS One b 12 2 :e Ketogenic diet as a metabolic therapy for mood disorders: evidence and developments. Neurosci Biobehav Rev —6.


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Nutritional ketosis affects metabolism and behavior in Sprague-Dawley rats in both control and chronic stress environments. Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats. J Neurochem 67 6 — Ketogenic diet metabolites reduce firing in central neurons by opening K ATP channels. J Neurosci — J Neurochem 5 — Puchalska P, Crawford PA.

Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics. Cell Metab 25 2 — Chronic in vitro ketosis is neuroprotective but not anti-convulsant. J Neurochem 4 — Science —4. Nat Med 21 3 —9. Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats. Anticonvulsant mechanisms of the ketogenic diet.

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Epilepsia — Mechanisms of action of antiseizure drugs and the ketogenic diet. Cold Spring Harb Perspect Med — Front Behav Neurosci Lutas A, Yellen G. The ketogenic diet: metabolic influences on brain excitability and epilepsy. Trends Neurosci 36 1 — The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev 59 2 — Do ketone bodies mediate the anti-seizure effects of the ketogenic diet? On the metabolism of exogenous ketones in humans. Front Physiol A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.

Ketone bodies, potential therapeutic uses.

Monamine Oxidase Inhibitors

Exogenous ketone supplementation decreased the lipopolysaccharide-induced increase in absence epileptic activity in Wistar Albino Glaxo Rijswijk rats. Clinical aspects of the ketogenic diet. Epilepsia 48 1 — Experience with the ketogenic diet in infants. Pediatrics 1 — Brunengraber H.

Potential of ketone body esters for parenteral and oral nutrition.


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  • Nutrition 13 3 —5. Kinetics, safety and tolerability of R hydroxybutyl R hydroxybutyrate in healthy adult subjects. Regul Toxicol Pharmacol a 63 3 —8. Cahill GF. Starvation in man. Clin Endocrinol Metab 5 2 — Fuel metabolism in starvation. Improving compliance in adults with epilepsy on a modified Atkins diet: a randomized trial. Seizure —8. Oral day and developmental toxicity studies of R hydroxybutyl R hydroxybutyrate.


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      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)
      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)
      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)
      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)
      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)
      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)
      Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa) Monoamine Oxidase Enzymes: Review and Overview (Journal of Neural Transmission. Supplementa)

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